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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta' and Ligand = 'BDBM50039075'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor alpha/beta


(Homo sapiens (Human))
BDBM50039075
PNG
(6-Methoxy-3-thiophen-3-yl-quinoline | CHEMBL303184)
Show SMILES COc1ccc2ncc(cc2c1)-c1ccsc1
Show InChI InChI=1S/C14H11NOS/c1-16-13-2-3-14-11(7-13)6-12(8-15-14)10-4-5-17-9-10/h2-9H,1H3
PDB

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Similars

PubMed
n/an/a 70n/an/an/an/an/an/a



Rhône-Poulenc Rorer Central Research

Curated by ChEMBL


Assay Description
Inhibition of human PDGF receptor phosphorylation; 0.05-0.07


J Med Chem 37: 2129-37 (1994)


BindingDB Entry DOI: 10.7270/Q29Z93Z8
More data for this
Ligand-Target Pair