Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM144587'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144587 (US8969583, 3) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C25H29N7O4S/c26-22(33)20-21(17-7-9-19(10-8-17)29-25(35)28-18-5-2-1-3-6-18)31-37-23(20)30-24(34)27-11-4-12-32-13-15-36-16-14-32/h1-3,5-10H,4,11-16H2,(H2,26,33)(H2,27,30,34)(H2,28,29,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
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