Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM144591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144591 (US8969583, 7) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)cc1 Show InChI InChI=1S/C26H31N7O4S/c1-17-3-7-19(8-4-17)29-26(36)30-20-9-5-18(6-10-20)22-21(23(27)34)24(38-32-22)31-25(35)28-11-2-12-33-13-15-37-16-14-33/h3-10H,2,11-16H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
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