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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM371376'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly(ADP-ribose) glycohydrolase


(Homo sapiens (Human))		BDBM371376
PNG
(1-Chloro-N-(1-methylcyclopropyl)isoquinoline-7-sul...)
Show SMILES CC1(CC1)NS(=O)(=O)c1ccc2ccnc(Cl)c2c1
Show InChI InChI=1S/C13H13ClN2O2S/c1-13(5-6-13)16-19(17,18)10-3-2-9-4-7-15-12(14)11(9)8-10/h2-4,7-8,16H,5-6H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 4.12E+3n/an/an/an/an/an/a



Istituto Superiore di Sanita



Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...

J Med Chem 51: 1058-62 (2008)


BindingDB Entry DOI: 10.7270/Q21R6SSM
More data for this
Ligand-Target Pair