BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM371519'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly(ADP-ribose) glycohydrolase


(Homo sapiens (Human))		BDBM371519
PNG
(N-[1-(Fluoromethyl)cyclopropyl]-1-[(1-methylpyrazo...)
Show SMILES Cc1nnc(Cn2c(=O)n(Cc3cnn(C)c3)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)s1
Show InChI InChI=1S/C21H22FN7O4S2/c1-13-24-25-18(34-13)11-29-19(30)16-7-15(35(32,33)26-21(12-22)5-6-21)3-4-17(16)28(20(29)31)10-14-8-23-27(2)9-14/h3-4,7-9,26H,5-6,10-12H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 16n/an/an/an/an/an/a



Istituto Superiore di Sanita



Assay Description
PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...

J Med Chem 51: 1058-62 (2008)


BindingDB Entry DOI: 10.7270/Q21R6SSM
More data for this
Ligand-Target Pair