Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM421431'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421431 (US10508086, Example 22 | US10995073, Example 22) Show SMILES CC(=O)OCCn1c2ccc(cc2n(C)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C16H21N3O5S/c1-11(20)24-9-8-19-13-5-4-12(10-14(13)18(3)15(19)21)25(22,23)17-16(2)6-7-16/h4-5,10,17H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.18E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421431 (US10508086, Example 22 | US10995073, Example 22) Show SMILES CC(=O)OCCn1c2ccc(cc2n(C)c1=O)S(=O)(=O)NC1(C)CC1 Show InChI InChI=1S/C16H21N3O5S/c1-11(20)24-9-8-19-13-5-4-12(10-14(13)18(3)15(19)21)25(22,23)17-16(2)6-7-16/h4-5,10,17H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.18E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair