Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM421434'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421434 (N-(1-Methylcyclopropyl)-1-[2-(3-methyl-2-oxo-imida...) Show SMILES CN1CCN(CC(=O)N2CCc3ccc(cc23)S(=O)(=O)NC2(C)CC2)C1=O Show InChI InChI=1S/C18H24N4O4S/c1-18(6-7-18)19-27(25,26)14-4-3-13-5-8-22(15(13)11-14)16(23)12-21-10-9-20(2)17(21)24/h3-4,11,19H,5-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.92E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421434 (N-(1-Methylcyclopropyl)-1-[2-(3-methyl-2-oxo-imida...) Show SMILES CN1CCN(CC(=O)N2CCc3ccc(cc23)S(=O)(=O)NC2(C)CC2)C1=O Show InChI InChI=1S/C18H24N4O4S/c1-18(6-7-18)19-27(25,26)14-4-3-13-5-8-22(15(13)11-14)16(23)12-21-10-9-20(2)17(21)24/h3-4,11,19H,5-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.92E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair