Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM421445'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421445 (US10508086, Example 36 | US10995073, Example 36) Show SMILES COc1cccc(Cn2c3ccc(cc3n(C)c2=O)S(=O)(=O)NC2(C)CC2)c1 Show InChI InChI=1S/C20H23N3O4S/c1-20(9-10-20)21-28(25,26)16-7-8-17-18(12-16)22(2)19(24)23(17)13-14-5-4-6-15(11-14)27-3/h4-8,11-12,21H,9-10,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.17E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM421445 (US10508086, Example 36 | US10995073, Example 36) Show SMILES COc1cccc(Cn2c3ccc(cc3n(C)c2=O)S(=O)(=O)NC2(C)CC2)c1 Show InChI InChI=1S/C20H23N3O4S/c1-20(9-10-20)21-28(25,26)16-7-8-17-18(12-16)22(2)19(24)23(17)13-14-5-4-6-15(11-14)27-3/h4-8,11-12,21H,9-10,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.17E+3	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair