Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM50541114'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Homo sapiens (Human))	BDBM50541114 (TETRAIDOFLUORESCEIN) Show SMILES OC(=O)c1ccccc1-c1c2cc(I)c(O)c(I)c2oc2c(I)c(=O)c(I)cc12 |(9.64,-9.16,;8.73,-7.92,;10.07,-7.15,;7.4,-7.15,;7.4,-5.61,;6.07,-4.84,;4.74,-5.61,;4.74,-7.15,;6.07,-7.92,;6.07,-9.46,;7.4,-10.23,;8.73,-9.46,;10.07,-10.23,;11.4,-9.46,;10.07,-11.77,;11.4,-12.54,;8.73,-12.54,;8.73,-14.08,;7.4,-11.77,;6.07,-12.54,;4.74,-11.77,;3.4,-12.54,;3.4,-14.08,;2.07,-11.77,;.73,-12.54,;2.07,-10.23,;.73,-9.46,;3.4,-9.46,;4.74,-10.23,)| Show InChI InChI=1S/C20H8I4O5/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25/h1-6,25H,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Science Curated by ChEMBL					Assay Description Inhibition of recombinant human PARG assessed as mono(ADP-R) release using PAR as substrate measured after 15 mins by HPLC analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115249 BindingDB Entry DOI: 10.7270/Q2XK8K38
					More data for this Ligand-Target Pair