Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM318021'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM318021 (8-Methyl-2-[4-[[5-trifluoromethyl)pyrimidin-2- yl]...) Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ncc(cn2)C(F)(F)F)CC1 Show InChI InChI=1S/C18H22F3N7O/c1-26-4-2-3-13-15(26)24-17(25-16(13)29)28-7-5-27(6-8-28)11-14-22-9-12(10-23-14)18(19,20)21/h9-10H,2-8,11H2,1H3,(H,24,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
					More data for this Ligand-Target Pair