Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM318028'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM318028 (2-[4-[(2- Methoxyphenyl)methyl]piperazin- 1-yl]-8-...) Show SMILES COc1ccccc1CN1CCN(CC1)c1nc2N(C)CCCc2c(=O)[nH]1 Show InChI InChI=1S/C20H27N5O2/c1-23-9-5-7-16-18(23)21-20(22-19(16)26)25-12-10-24(11-13-25)14-15-6-3-4-8-17(15)27-2/h3-4,6,8H,5,7,9-14H2,1-2H3,(H,21,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.4	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
					More data for this Ligand-Target Pair