Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM318036'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM318036 (2-[[4-(8-Methyl-4-oxo-3,5,6,7-tetrahydropyrido[2,3...) Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ccccc2C#N)CC1 Show InChI InChI=1S/C20H24N6O/c1-24-8-4-7-17-18(24)22-20(23-19(17)27)26-11-9-25(10-12-26)14-16-6-3-2-5-15(16)13-21/h2-3,5-6H,4,7-12,14H2,1H3,(H,22,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.8	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
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