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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM404341'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-1


(Homo sapiens (Human))		BDBM404341
PNG
(2-Chloro-6-{3-[4-(4-methoxy-benzoyl)-piperidin-1-y...)
Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(Cc2cccc(Cl)c2C#N)C1=O
Show InChI InChI=1S/C25H26ClN3O3/c1-32-20-7-5-17(6-8-20)24(30)18-9-12-28(13-10-18)23-11-14-29(25(23)31)16-19-3-2-4-22(26)21(19)15-27/h2-8,18,23H,9-14,16H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 162n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...

US Patent USRE46942 (2018)


BindingDB Entry DOI: 10.7270/Q2VX0JVH
More data for this
Ligand-Target Pair