Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM318007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM318007 (8-Methyl-2-[4-(pyrimidin-2-ylmethyl)piperazin-1-yl...) Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ncccn2)CC1 Show InChI InChI=1S/C17H23N7O/c1-22-7-2-4-13-15(22)20-17(21-16(13)25)24-10-8-23(9-11-24)12-14-18-5-3-6-19-14/h3,5-6H,2,4,7-12H2,1H3,(H,20,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.95	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM318007 (8-Methyl-2-[4-(pyrimidin-2-ylmethyl)piperazin-1-yl...) Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ncccn2)CC1 Show InChI InChI=1S/C17H23N7O/c1-22-7-2-4-13-15(22)20-17(21-16(13)25)24-10-8-23(9-11-24)12-14-18-5-3-6-19-14/h3,5-6H,2,4,7-12H2,1H3,(H,20,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.7	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
					More data for this Ligand-Target Pair