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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM318020'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-2


(Homo sapiens (Human))		BDBM318020
PNG
(8-Methyl-2-[4-[(4- methylpyrimidin-2- yl)methyl]pi...)
Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2nccc(C)n2)CC1
Show InChI InChI=1S/C18H25N7O/c1-13-5-6-19-15(20-13)12-24-8-10-25(11-9-24)18-21-16-14(17(26)22-18)4-3-7-23(16)2/h5-6H,3-4,7-12H2,1-2H3,(H,21,22,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11.7n/an/an/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...

US Patent US9624218 (2017)


BindingDB Entry DOI: 10.7270/Q26112CZ
More data for this
Ligand-Target Pair