Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM50505333![]() (CHEMBL4437173) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Healthcare KGaA Curated by ChEMBL | Assay Description Inhibition of GST-tagged recombinant human TNKS2 (667 to 1166 end residues) expressed in baculovirus infected sf9 cells using biotinylated substrate ... | J Med Chem 62: 7897-7909 (2019) Article DOI: 10.1021/acs.jmedchem.9b00656 BindingDB Entry DOI: 10.7270/Q2FJ2M28 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM50505333![]() (CHEMBL4437173) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cells | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM50505333![]() (CHEMBL4437173) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM50505333![]() (CHEMBL4437173) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Healthcare KGaA Curated by ChEMBL | Assay Description Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ... | J Med Chem 62: 7897-7909 (2019) Article DOI: 10.1021/acs.jmedchem.9b00656 BindingDB Entry DOI: 10.7270/Q2FJ2M28 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |