Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50557890'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50557890 (CHEMBL4761317) Show SMILES O=C(Nc1ccncc1)[C@H]1CC[C@H](Cn2c(=O)n(Cc3ccccc3C#N)c3cccnc3c2=O)CC1 |r,wU:9.9,wD:12.13,(14.67,-7.68,;14.67,-6.14,;16,-5.37,;17.33,-6.14,;17.33,-7.68,;18.66,-8.45,;20,-7.68,;19.99,-6.13,;18.66,-5.37,;13.33,-5.37,;12,-6.13,;10.67,-5.37,;10.68,-3.82,;9.34,-3.06,;8.01,-3.83,;8.01,-5.39,;9.35,-6.16,;6.67,-6.17,;6.67,-7.71,;5.34,-8.48,;4.01,-7.71,;2.68,-8.48,;2.68,-10.02,;4.03,-10.79,;5.35,-10.01,;6.7,-10.77,;8.04,-11.54,;5.33,-5.4,;3.99,-6.16,;2.66,-5.39,;2.66,-3.85,;3.99,-3.08,;5.32,-3.84,;6.66,-3.06,;6.65,-1.51,;12,-3.05,;13.33,-3.82,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00160 BindingDB Entry DOI: 10.7270/Q2W099KF
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