Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50557892'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50557892 (CHEMBL4757303) Show SMILES Cc1cccc2n(Cc3cccc(c3C#N)C(F)(F)F)c(=O)n(C[C@H]3CC[C@@H](CC3)C(=O)Nc3ccnnc3)c(=O)c12 |r,wU:27.31,wD:24.24,(49.57,-1.24,;49.58,-2.78,;48.25,-3.55,;48.25,-5.1,;49.58,-5.87,;50.92,-5.1,;52.26,-5.87,;52.27,-7.41,;50.93,-8.18,;49.6,-7.41,;48.27,-8.19,;48.27,-9.73,;49.62,-10.49,;50.94,-9.72,;52.29,-10.48,;53.63,-11.24,;49.63,-12.03,;48.22,-12.73,;51.22,-12.17,;49.47,-13.48,;53.61,-5.09,;54.94,-5.86,;53.6,-3.54,;54.93,-2.76,;56.27,-3.53,;56.26,-5.07,;57.59,-5.84,;58.93,-5.07,;58.93,-3.53,;57.59,-2.76,;60.26,-5.84,;60.26,-7.38,;61.59,-5.07,;62.93,-5.84,;64.25,-5.07,;65.59,-5.84,;65.59,-7.38,;64.25,-8.15,;62.92,-7.38,;52.25,-2.76,;52.24,-1.21,;50.91,-3.55,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00160 BindingDB Entry DOI: 10.7270/Q2W099KF
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