Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50579958'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579958 (CHEMBL5070921 | US11926614, Example 68) Show SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2ccccn2)n1-c1ccccc1 |r,wU:15.18,wD:13.13,(33.18,-42.09,;34.08,-40.85,;35.61,-41.02,;36.51,-39.77,;38.04,-39.93,;38.94,-38.69,;38.32,-37.3,;36.79,-37.13,;35.89,-38.37,;39.22,-36.06,;38.75,-34.59,;39.98,-33.68,;41.24,-34.59,;42.7,-34.11,;44.07,-34.82,;44.78,-33.44,;43.4,-32.74,;46.25,-32.97,;46.57,-31.46,;45.42,-30.43,;48.04,-30.98,;48.34,-29.47,;49.81,-28.99,;50.97,-30.02,;50.65,-31.53,;49.18,-32.01,;40.76,-36.06,;41.66,-37.3,;41.03,-38.7,;41.93,-39.94,;43.46,-39.78,;44.08,-38.37,;43.18,-37.14,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579958 (CHEMBL5070921 | US11926614, Example 68) Show SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2ccccn2)n1-c1ccccc1 |r,wU:15.18,wD:13.13,(33.18,-42.09,;34.08,-40.85,;35.61,-41.02,;36.51,-39.77,;38.04,-39.93,;38.94,-38.69,;38.32,-37.3,;36.79,-37.13,;35.89,-38.37,;39.22,-36.06,;38.75,-34.59,;39.98,-33.68,;41.24,-34.59,;42.7,-34.11,;44.07,-34.82,;44.78,-33.44,;43.4,-32.74,;46.25,-32.97,;46.57,-31.46,;45.42,-30.43,;48.04,-30.98,;48.34,-29.47,;49.81,-28.99,;50.97,-30.02,;50.65,-31.53,;49.18,-32.01,;40.76,-36.06,;41.66,-37.3,;41.03,-38.7,;41.93,-39.94,;43.46,-39.78,;44.08,-38.37,;43.18,-37.14,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NAD				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01264 BindingDB Entry DOI: 10.7270/Q21R6VDH
					More data for this Ligand-Target Pair