Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyamine deacetylase HDAC10' and Ligand = 'BDBM50242139'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50242139 (CHEMBL4078721) Show SMILES CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(CNC(=O)C[C@H](OC1=O)\C=C\CCSCCS)n2 |r,c:11| Show InChI InChI=1S/C23H32N4O4S4/c1-14(2)19-21(29)31-15(6-4-5-8-33-9-7-32)10-17(28)24-11-18-25-16(12-34-18)20-27-23(3,13-35-20)22(30)26-19/h4,6,12,14-15,19,32H,5,7-11,13H2,1-3H3,(H,24,28)(H,26,30)/b6-4+/t15-,19+,23+/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC10 (1 to 481 residues) expressed in baculovirus infected Sf9 insect cells using B...				Bioorg Med Chem 25: 3077-3086 (2017) Article DOI: 10.1016/j.bmc.2017.03.071 BindingDB Entry DOI: 10.7270/Q2M047MP
					More data for this Ligand-Target Pair