Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM291876'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM291876 (8-(4-(difluoromethyl)pyrimidin-5-yl)-N-((5-fluoro-...) Show SMILES FC(F)c1ncncc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI InChI=1S/C19H14F3N7O/c20-14-1-2-15-10(3-4-30-15)11(14)6-24-19-25-7-13(18-28-27-9-29(18)19)12-5-23-8-26-16(12)17(21)22/h1-2,5,7-9,17H,3-4,6H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JNH
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM291876 (8-(4-(difluoromethyl)pyrimidin-5-yl)-N-((5-fluoro-...) Show SMILES FC(F)c1ncncc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI InChI=1S/C19H14F3N7O/c20-14-1-2-15-10(3-4-30-15)11(14)6-24-19-25-7-13(18-28-27-9-29(18)19)12-5-23-8-26-16(12)17(21)22/h1-2,5,7-9,17H,3-4,6H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JNH
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM291876 (8-(4-(difluoromethyl)pyrimidin-5-yl)-N-((5-fluoro-...) Show SMILES FC(F)c1ncncc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12 Show InChI InChI=1S/C19H14F3N7O/c20-14-1-2-15-10(3-4-30-15)11(14)6-24-19-25-7-13(18-28-27-9-29(18)19)12-5-23-8-26-16(12)17(21)22/h1-2,5,7-9,17H,3-4,6H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JNH
					More data for this Ligand-Target Pair