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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polymerase acidic protein' and Ligand = 'BDBM50509163'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polymerase acidic protein


(Hepatitis C virus)
BDBM50509163
PNG
(CHEMBL4555466)
Show SMILES Cc1cc(ccc1-c1cc(=O)c(O)c([nH]1)C(O)=O)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N5O4/c1-6-4-7(13-16-18-19-17-13)2-3-8(6)9-5-10(20)12(21)11(15-9)14(22)23/h2-5,21H,1H3,(H,15,20)(H,22,23)(H,16,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...


J Med Chem 62: 9438-9449 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00747
BindingDB Entry DOI: 10.7270/Q27M0C7P
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Polymerase acidic protein


(Hepatitis C virus)
BDBM50509163
PNG
(CHEMBL4555466)
Show SMILES Cc1cc(ccc1-c1cc(=O)c(O)c([nH]1)C(O)=O)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N5O4/c1-6-4-7(13-16-18-19-17-13)2-3-8(6)9-5-10(20)12(21)11(15-9)14(22)23/h2-5,21H,1H3,(H,15,20)(H,22,23)(H,16,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...


J Med Chem 62: 9438-9449 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00747
BindingDB Entry DOI: 10.7270/Q27M0C7P
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)