Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM50507231'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase basic protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50507231 (CHEMBL4453678) Show SMILES OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(ncc1F)-n1ccc2ncc(F)cc12 |r,wU:3.2,wD:10.12,(9.5,-36.14,;10.83,-36.9,;12.16,-36.12,;10.84,-38.44,;12.19,-39.21,;12.2,-40.75,;10.87,-41.53,;9.54,-40.77,;10.3,-39.48,;11.41,-40.38,;9.53,-39.22,;8.2,-38.47,;6.89,-39.25,;7.36,-40.7,;6.35,-41.83,;4.85,-41.54,;4.36,-40.08,;5.39,-38.94,;4.92,-37.49,;6.83,-43.28,;5.93,-44.54,;6.84,-45.78,;8.3,-45.3,;9.64,-46.07,;10.97,-45.3,;10.97,-43.75,;12.3,-42.97,;9.64,-42.98,;8.3,-43.76,)| Show InChI InChI=1S/C20H19F2N5O2/c21-12-7-15-14(23-8-12)5-6-27(15)20-24-9-13(22)18(26-20)25-17-11-3-1-10(2-4-11)16(17)19(28)29/h5-11,16-17H,1-4H2,(H,28,29)(H,24,25,26)/t10?,11?,16-,17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of PB2 in Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as reduction in virus induced cell death after 5 days by ...				Eur J Med Chem 162: 249-265 (2019) Article DOI: 10.1016/j.ejmech.2018.11.015 BindingDB Entry DOI: 10.7270/Q2PG1W2P
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