Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM50507232'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase basic protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50507232 (CHEMBL4513835) Show SMILES OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(ncc1F)-c1c[nH]c2ccc(F)cc12 |r,wU:3.2,wD:10.12,(21.38,-34.97,;22.71,-35.73,;24.04,-34.95,;22.72,-37.27,;24.07,-38.04,;24.08,-39.58,;22.75,-40.36,;21.42,-39.6,;22.18,-38.31,;23.29,-39.21,;21.41,-38.05,;20.08,-37.3,;18.77,-38.08,;19.24,-39.52,;18.23,-40.66,;16.73,-40.36,;16.24,-38.91,;17.27,-37.77,;16.8,-36.32,;18.71,-42.11,;17.81,-43.36,;18.72,-44.61,;20.18,-44.12,;21.52,-44.9,;22.85,-44.12,;22.85,-42.57,;24.18,-41.8,;21.52,-41.81,;20.18,-42.59,)| Show InChI InChI=1S/C21H20F2N4O2/c22-12-5-6-16-13(7-12)14(8-24-16)19-25-9-15(23)20(27-19)26-18-11-3-1-10(2-4-11)17(18)21(28)29/h5-11,17-18,24H,1-4H2,(H,28,29)(H,25,26,27)/t10?,11?,17-,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of PB2 in Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as reduction in virus induced cell death after 5 days by ...				Eur J Med Chem 162: 249-265 (2019) Article DOI: 10.1016/j.ejmech.2018.11.015 BindingDB Entry DOI: 10.7270/Q2PG1W2P
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