Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM50507243'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase basic protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50507243 (CHEMBL4522400) Show SMILES Cc1cnc2c(N[C@H]3C4CCC(CC4)[C@@H]3C(O)=O)nc(nc2c1)-c1c[nH]c2ncc(F)cc12 |r,wU:14.16,wD:7.6,(2.58,-19.43,;4.08,-19.74,;5.1,-18.59,;6.61,-18.9,;7.08,-20.36,;8.58,-20.67,;9.9,-19.89,;11.23,-20.64,;11.24,-22.2,;12.57,-22.96,;13.91,-22.18,;13.9,-20.63,;13.12,-21.81,;12,-20.9,;12.55,-19.86,;12.54,-18.31,;11.2,-17.55,;13.88,-17.53,;9.06,-22.12,;8.04,-23.26,;6.53,-22.97,;6.05,-21.5,;4.56,-21.19,;8.52,-24.72,;7.62,-25.98,;8.53,-27.23,;10,-26.74,;11.34,-27.51,;12.68,-26.74,;12.68,-25.18,;14.02,-24.4,;11.34,-24.41,;10,-25.19,)| Show InChI InChI=1S/C24H23FN6O2/c1-11-6-17-20(26-8-11)23(30-19-13-4-2-12(3-5-13)18(19)24(32)33)31-22(29-17)16-10-28-21-15(16)7-14(25)9-27-21/h6-10,12-13,18-19H,2-5H2,1H3,(H,27,28)(H,32,33)(H,29,30,31)/t12?,13?,18-,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of PB2 in Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as reduction in virus induced cell death after 5 days by ...				Eur J Med Chem 162: 249-265 (2019) Article DOI: 10.1016/j.ejmech.2018.11.015 BindingDB Entry DOI: 10.7270/Q2PG1W2P
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