Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM50507251'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase basic protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50507251 (CHEMBL4469158) Show SMILES OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(nc2CSCc12)-c1c[nH]c2ncc(F)cc12 |r,wU:3.2,wD:10.12,(41.42,-45.38,;42.75,-46.14,;44.09,-45.36,;42.77,-47.68,;44.11,-48.45,;44.12,-50,;42.79,-50.77,;41.46,-50.01,;42.22,-48.72,;43.34,-49.63,;41.45,-48.46,;40.12,-47.71,;38.8,-48.49,;39.28,-49.94,;38.26,-51.08,;36.76,-50.78,;36.27,-49.33,;34.87,-48.7,;35.03,-47.17,;36.54,-46.85,;37.3,-48.18,;38.74,-52.53,;37.84,-53.79,;38.75,-55.03,;40.22,-54.55,;41.56,-55.32,;42.9,-54.55,;42.89,-52.99,;44.23,-52.22,;41.56,-52.23,;40.21,-53.01,)| Show InChI InChI=1S/C22H22FN5O2S/c23-12-5-13-14(7-25-19(13)24-6-12)20-26-16-9-31-8-15(16)21(28-20)27-18-11-3-1-10(2-4-11)17(18)22(29)30/h5-7,10-11,17-18H,1-4,8-9H2,(H,24,25)(H,29,30)(H,26,27,28)/t10?,11?,17-,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of PB2 in Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as reduction in virus induced cell death after 5 days by ...				Eur J Med Chem 162: 249-265 (2019) Article DOI: 10.1016/j.ejmech.2018.11.015 BindingDB Entry DOI: 10.7270/Q2PG1W2P
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