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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM552439'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polymerase basic protein 2


(Influenza A virus (strain A/WS/1933 H1N1))
BDBM552439
PNG
((18′*R,*E)-3′,4′-difluoro-12R...)
Show SMILES Cc1ccccc1[C@@H]1N2CN(C(=O)c3c(O)c(=O)ccn23)C2(CCC2)\C=C\COc2c(F)c(F)ccc12 |r,t:29|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
EN PA FRET inhibition assay was performed using a 19 nucleotide synthetic oligoribonucleotide substrate: 5′-FAM-AUUUUGUUUUUAAUAUUUC-BHQ-3′...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2P272BG
More data for this
Ligand-Target Pair
Polymerase basic protein 2


(Influenza A virus (strain A/WS/1933 H1N1))
BDBM552439
PNG
((18′*R,*E)-3′,4′-difluoro-12R...)
Show SMILES Cc1ccccc1[C@@H]1N2CN(C(=O)c3c(O)c(=O)ccn23)C2(CCC2)\C=C\COc2c(F)c(F)ccc12 |r,t:29|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.20n/an/an/an/a


TBA

Assay Description
Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2P272BG
More data for this
Ligand-Target Pair