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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50351096'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50351096
PNG
(ASCORBIC ACID)
Show SMILES OC[C@H](O)[C@H]1OC(=O)C(=O)C1O |r|
Show InChI InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-3,5,7-9H,1H2/t2-,3?,5+/m0/s1
UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.40E+5n/an/an/an/an/an/a



Catholic University of C£rdoba

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis


Bioorg Med Chem 19: 3474-82 (2011)


Article DOI: 10.1016/j.bmc.2011.04.025
BindingDB Entry DOI: 10.7270/Q22Z18DZ
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50351096
PNG
(ASCORBIC ACID)
Show SMILES OC[C@H](O)[C@H]1OC(=O)C(=O)C1O |r|
Show InChI InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-3,5,7-9H,1H2/t2-,3?,5+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.44E+5n/an/an/an/an/an/a



University of Pretoria

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...


J Nat Prod 81: 49-56 (2018)


Article DOI: 10.1021/acs.jnatprod.7b00564
BindingDB Entry DOI: 10.7270/Q2H70JBS
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50351096
PNG
(ASCORBIC ACID)
Show SMILES OC[C@H](O)[C@H]1OC(=O)C(=O)C1O |r|
Show InChI InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-3,5,7-9H,1H2/t2-,3?,5+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.87E+5n/an/an/an/an/an/a



Nicolaus Copernicus University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-dopa as substrate by spectrophotometric method


Eur J Med Chem 184: (2019)


Article DOI: 10.1016/j.ejmech.2019.111765
BindingDB Entry DOI: 10.7270/Q25B05XS
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50351096
PNG
(ASCORBIC ACID)
Show SMILES OC[C@H](O)[C@H]1OC(=O)C(=O)C1O |r|
Show InChI InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-3,5,7-9H,1H2/t2-,3?,5+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.87E+5n/an/an/an/an/an/a



Nicolaus Copernicus University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric method


Eur J Med Chem 175: 162-171 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.006
BindingDB Entry DOI: 10.7270/Q2794815
More data for this
Ligand-Target Pair