Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50442881 (SILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 BindingDB Entry DOI: 10.7270/Q2PV6PTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50442881 (SILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 BindingDB Entry DOI: 10.7270/Q2PV6PTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50442881 (SILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 BindingDB Entry DOI: 10.7270/Q2PV6PTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50442881 (SILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 BindingDB Entry DOI: 10.7270/Q2PV6PTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50442881 (SILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 BindingDB Entry DOI: 10.7270/Q2PV6PTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM50442881 (SILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 BindingDB Entry DOI: 10.7270/Q2PV6PTR | |||||||||||
More data for this Ligand-Target Pair |