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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50452914'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50452914
PNG
(CHEMBL4216024)
Show SMILES Oc1cccc(c1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C18H19FN2O2/c19-16-6-4-14(5-7-16)13-20-8-10-21(11-9-20)18(23)15-2-1-3-17(22)12-15/h1-7,12,22H,8-11,13H2
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Universit� di Messina

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addition...

J Med Chem 61: 3908-3917 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01745
BindingDB Entry DOI: 10.7270/Q2V127DR
More data for this
Ligand-Target Pair