Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50491382'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50491382 (CHEMBL2380378) Show SMILES COc1ccc(NC2=NC(=O)\C(S2)=C\c2cn(nc2-c2ccc(Br)cc2)-c2ccccc2)c(OC)c1 |t:7| Show InChI InChI=1S/C27H21BrN4O3S/c1-34-21-12-13-22(23(15-21)35-2)29-27-30-26(33)24(36-27)14-18-16-32(20-6-4-3-5-7-20)31-25(18)17-8-10-19(28)11-9-17/h3-16H,1-2H3,(H,29,30,33)/b24-14-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bahirji Smarak Mahavidyalaya Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase diphenolase activity assessed as L-DOPA conversion to dopachrome by Lineweaver-Burk plot analysis				Bioorg Med Chem 21: 2772-7 (2013) Article DOI: 10.1016/j.bmc.2012.12.053 BindingDB Entry DOI: 10.7270/Q2G44T6G
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50491382 (CHEMBL2380378) Show SMILES COc1ccc(NC2=NC(=O)\C(S2)=C\c2cn(nc2-c2ccc(Br)cc2)-c2ccccc2)c(OC)c1 |t:7| Show InChI InChI=1S/C27H21BrN4O3S/c1-34-21-12-13-22(23(15-21)35-2)29-27-30-26(33)24(36-27)14-18-16-32(20-6-4-3-5-7-20)31-25(18)17-8-10-19(28)11-9-17/h3-16H,1-2H3,(H,29,30,33)/b24-14-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bahirji Smarak Mahavidyalaya Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins by spectrophotometric analysis				Bioorg Med Chem 21: 2772-7 (2013) Article DOI: 10.1016/j.bmc.2012.12.053 BindingDB Entry DOI: 10.7270/Q2G44T6G
					More data for this Ligand-Target Pair