Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50513187'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50513187 (CHEMBL4583240) Show SMILES [H][C@]12CC[C@]([H])(C\C(C1)=N/Nc1nc(cs1)-c1ccc(Cl)cc1Cl)N2C |r,TLB:9:7:24:2.3| Show InChI InChI=1S/C17H18Cl2N4S/c1-23-12-3-4-13(23)8-11(7-12)21-22-17-20-16(9-24-17)14-5-2-10(18)6-15(14)19/h2,5-6,9,12-13H,3-4,7-8H2,1H3,(H,20,22)/b21-11-/t12-,13+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nicolaus Copernicus University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric method				Eur J Med Chem 175: 162-171 (2019) Article DOI: 10.1016/j.ejmech.2019.05.006 BindingDB Entry DOI: 10.7270/Q2794815
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