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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50004676'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50004676
PNG
(1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4...)
Show SMILES OC(Cn1ccnc1)(c1ccc(F)cc1)c1ccc(cc1)-c1ccncc1
Show InChI InChI=1S/C22H18FN3O/c23-21-7-5-20(6-8-21)22(27,15-26-14-13-25-16-26)19-3-1-17(2-4-19)18-9-11-24-12-10-18/h1-14,16,27H,15H2
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MMDB

KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



Du Pont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 5-lipoxygenase of RBL-1 cell line

J Med Chem 35: 3148-55 (1992)


BindingDB Entry DOI: 10.7270/Q2V69HJ7
More data for this
Ligand-Target Pair