BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50037802'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50037802
PNG
(CHEMBL120107 | N-Hydroxy-2,6-dimethoxy-N-[1-(2-phe...)
Show SMILES COc1cccc(OC)c1C(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1ccccc1
Show InChI InChI=1S/C25H23NO5/c1-16(26(28)25(27)24-21(29-2)10-7-11-22(24)30-3)18-12-13-20-19(14-18)15-23(31-20)17-8-5-4-6-9-17/h4-16,28H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay

J Med Chem 37: 3663-7 (1994)


BindingDB Entry DOI: 10.7270/Q27943Q2
More data for this
Ligand-Target Pair