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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50037806'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50037806
PNG
(CHEMBL123177 | Thiophene-2-carboxylic acid hydroxy...)
Show SMILES CC(N(O)C(=O)c1cccs1)c1ccc2oc(cc2c1)-c1ccccc1
Show InChI InChI=1S/C21H17NO3S/c1-14(22(24)21(23)20-8-5-11-26-20)16-9-10-18-17(12-16)13-19(25-18)15-6-3-2-4-7-15/h2-14,24H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 250n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay

J Med Chem 37: 3663-7 (1994)


BindingDB Entry DOI: 10.7270/Q27943Q2
More data for this
Ligand-Target Pair