Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50055118'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50055118 (CHEMBL356563 | N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(...) Show SMILES COc1ccc(COc2cccc3C(CCCc23)N(O)C(N)=O)cc1 Show InChI InChI=1S/C19H22N2O4/c1-24-14-10-8-13(9-11-14)12-25-18-7-3-4-15-16(18)5-2-6-17(15)21(23)19(20)22/h3-4,7-11,17,23H,2,5-6,12H2,1H3,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
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