Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50055127'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50055127 (CHEMBL148298 | bicyclic N-hydroxy urea derivatives) Show SMILES NC(=O)N(O)C1CCCc2cc(OCc3ccc4ccccc4c3)ccc12 Show InChI InChI=1S/C22H22N2O3/c23-22(25)24(26)21-7-3-6-18-13-19(10-11-20(18)21)27-14-15-8-9-16-4-1-2-5-17(16)12-15/h1-2,4-5,8-13,21,26H,3,6-7,14H2,(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
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