Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50055133'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50055133 (CHEMBL146537 | N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(...) Show SMILES NC(=O)N(O)C1CCCc2cc(OCc3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C18H19ClN2O3/c19-14-6-4-12(5-7-14)11-24-15-8-9-16-13(10-15)2-1-3-17(16)21(23)18(20)22/h4-10,17,23H,1-3,11H2,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
					More data for this Ligand-Target Pair