Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50085209'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50085209 (CHEMBL422536 | {Cyclohexyl-[4-(quinolin-2-ylmethox...) Show SMILES OC(=O)C(=N\OC(C1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1)\c1ccccc1 Show InChI InChI=1S/C31H30N2O4/c34-31(35)29(23-10-3-1-4-11-23)33-37-30(24-12-5-2-6-13-24)25-16-19-27(20-17-25)36-21-26-18-15-22-9-7-8-14-28(22)32-26/h1,3-4,7-11,14-20,24,30H,2,5-6,12-13,21H2,(H,34,35)/b33-29+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair