Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50085229'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50085229 (CHEMBL159516 | {3-Methyl-3-phenyl-1-[4-(quinolin-2...) Show SMILES CC(C)(CC(O\N=C\C(O)=O)c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccccc1 Show InChI InChI=1S/C29H28N2O4/c1-29(2,23-9-4-3-5-10-23)18-27(35-30-19-28(32)33)22-13-16-25(17-14-22)34-20-24-15-12-21-8-6-7-11-26(21)31-24/h3-17,19,27H,18,20H2,1-2H3,(H,32,33)/b30-19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay				J Med Chem 43: 690-705 (2000) BindingDB Entry DOI: 10.7270/Q2HD7WCR
					More data for this Ligand-Target Pair