Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50144625![]() (1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against 5-lipoxygenase in an RBL-2H3 cell lysate | Bioorg Med Chem Lett 14: 2265-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.005 BindingDB Entry DOI: 10.7270/Q2BV7G2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50144625![]() (1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Organon Laboratories Curated by ChEMBL | Assay Description Inhibition constant against arachidonate 5-lipoxygenase | J Med Chem 48: 6523-43 (2005) Article DOI: 10.1021/jm058225d BindingDB Entry DOI: 10.7270/Q2SF2WZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50144625![]() (1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assay | Bioorg Med Chem Lett 14: 2265-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.005 BindingDB Entry DOI: 10.7270/Q2BV7G2P | |||||||||||
More data for this Ligand-Target Pair |