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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50279846'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))		BDBM50279846
PNG
((E)-N-Hydroxy-N-methyl-3-(10H-phenoxazin-2-yl)-acr...)
Show SMILES CN(O)C(=O)\C=C\c1ccc2Oc3ccccc3Nc2c1
Show InChI InChI=1S/C16H14N2O3/c1-18(20)16(19)9-7-11-6-8-15-13(10-11)17-12-4-2-3-5-14(12)21-15/h2-10,17,20H,1H3/b9-7+
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PC sid
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Article
n/an/a 85n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-lipoxygenase in vitro (guinea pig PMN)

Bioorg Med Chem Lett 1: 107-110 (1991)


Article DOI: 10.1016/S0960-894X(00)80241-3
BindingDB Entry DOI: 10.7270/Q2DF6R3J
More data for this
Ligand-Target Pair