Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50280049'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280049 (5-Methyl-2-[2-(10H-phenothiazin-3-yloxy)-ethyl]-2,...) Show SMILES Cc1cc(=O)n(CCOc2ccc3Nc4ccccc4Sc3c2)[nH]1 Show InChI InChI=1S/C18H17N3O2S/c1-12-10-18(22)21(20-12)8-9-23-13-6-7-15-17(11-13)24-16-5-3-2-4-14(16)19-15/h2-7,10-11,19-20H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMN				Bioorg Med Chem Lett 2: 59-62 (1992) Article DOI: 10.1016/S0960-894X(00)80655-1 BindingDB Entry DOI: 10.7270/Q2FB52TK
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