Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50369677![]() (CHEMBL4172824) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Campania "Luigi Vanvitelli" Curated by ChEMBL | Assay Description Inhibition of 5-LOX (unknown origin) | Eur J Med Chem 153: 65-72 (2018) Article DOI: 10.1016/j.ejmech.2017.10.020 BindingDB Entry DOI: 10.7270/Q26H4M0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50369677![]() (CHEMBL4172824) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Advanced Sciences Curated by ChEMBL | Assay Description Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric method | Bioorg Med Chem 27: 3745-3759 (2019) Article DOI: 10.1016/j.bmc.2019.06.040 BindingDB Entry DOI: 10.7270/Q2251NNQ | |||||||||||
More data for this Ligand-Target Pair |