Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50394763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50394763 (CHEMBL2163373) Show SMILES COc1ccc(\C=C2/N=C(OC2=O)c2ccc(Cl)c(c2)[N+]([O-])=O)c(OC)c1OC |c:8| Show InChI InChI=1S/C19H15ClN2O7/c1-26-15-7-5-10(16(27-2)17(15)28-3)8-13-19(23)29-18(21-13)11-4-6-12(20)14(9-11)22(24)25/h4-9H,1-3H3/b13-8-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL2-DE3 incubated 10 mins before substrate addition by fluorescence spectrophotom...				J Med Chem 55: 2597-605 (2012) Article DOI: 10.1021/jm201497k BindingDB Entry DOI: 10.7270/Q20P115J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50394763 (CHEMBL2163373) Show SMILES COc1ccc(\C=C2/N=C(OC2=O)c2ccc(Cl)c(c2)[N+]([O-])=O)c(OC)c1OC |c:8| Show InChI InChI=1S/C19H15ClN2O7/c1-26-15-7-5-10(16(27-2)17(15)28-3)8-13-19(23)29-18(21-13)11-4-6-12(20)14(9-11)22(24)25/h4-9H,1-3H3/b13-8-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human 5-LOX in A23187-induced human whole blood assessed as reduction in LTB4 production pre-incubated for 20 mins before A23187 additi...				J Med Chem 55: 2597-605 (2012) Article DOI: 10.1021/jm201497k BindingDB Entry DOI: 10.7270/Q20P115J
					More data for this Ligand-Target Pair