Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50403392'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50403392 (CHEMBL17293) Show SMILES NC(=O)N(O)Cc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C22H18FN5O2/c23-18-7-5-15(6-8-18)19-20(16-9-11-25-12-10-16)27-21(26-19)17-3-1-14(2-4-17)13-28(30)22(24)29/h1-12,30H,13H2,(H2,24,29)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytes				Bioorg Med Chem Lett 5: 1171-1176 (1995) Article DOI: 10.1016/0960-894X(95)00189-Z BindingDB Entry DOI: 10.7270/Q28S4PV1
					More data for this Ligand-Target Pair