BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50512033'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50512033
PNG
(CHEMBL4447638)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(=O)N1CCOCC1
Show InChI InChI=1S/C20H19FN4O4S/c21-15-3-1-14(2-4-15)19-13-18(20(26)24-9-11-29-12-10-24)23-25(19)16-5-7-17(8-6-16)30(22,27)28/h1-8,13H,9-12H2,(H2,22,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 890n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of Sprague-Dawley rat 5-LOX assessed as calcium ionophore A23187-stimulated LTB4 production preincubated for 30 mins followed by calcium i...

Eur J Med Chem 169: 168-184 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.008
BindingDB Entry DOI: 10.7270/Q2K077MH
More data for this
Ligand-Target Pair