Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15' and Ligand = 'BDBM22240'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX15 (Oryctolagus cuniculus (rabbit))	BDBM22240 (4,5-di-substituted imidazole, 14e | N-{2-[5-(4-met...) Show SMILES CCCCCc1ccc(cc1)S(=O)(=O)NCCc1[nH]cnc1-c1ccc(OC)cc1 Show InChI InChI=1S/C23H29N3O3S/c1-3-4-5-6-18-7-13-21(14-8-18)30(27,28)26-16-15-22-23(25-17-24-22)19-9-11-20(29-2)12-10-19/h7-14,17,26H,3-6,15-16H2,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 17: 5115-20 (2007) Article DOI: 10.1016/j.bmcl.2007.07.011 BindingDB Entry DOI: 10.7270/Q2XW4H31
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