Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15' and Ligand = 'BDBM50105865'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50105865 (CHEMBL3597762) Show SMILES CC(=O)n1ccc(n1)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C12H9Cl2N3O2/c1-7(18)17-5-4-11(16-17)12(19)15-8-2-3-9(13)10(14)6-8/h2-6H,1H3,(H,15,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	292	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assay				Bioorg Med Chem Lett 25: 3017-23 (2015) Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50105865 (CHEMBL3597762) Show SMILES CC(=O)n1ccc(n1)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C12H9Cl2N3O2/c1-7(18)17-5-4-11(16-17)12(19)15-8-2-3-9(13)10(14)6-8/h2-6H,1H3,(H,15,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	428	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate				Bioorg Med Chem Lett 25: 3017-23 (2015) Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3
					More data for this Ligand-Target Pair