Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50027656 (CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human thymidylate synthase expressed in Escherichia coli using 6R,S-tetrahydrofolate and dUMP as substrate by spectrophotometric analys... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116136 BindingDB Entry DOI: 10.7270/Q2M330JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15B (Rattus norvegicus) | BDBM50027656 (CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method | Bioorg Med Chem Lett 27: 1602-1607 (2017) Article DOI: 10.1016/j.bmcl.2017.02.018 BindingDB Entry DOI: 10.7270/Q2P55QR0 | |||||||||||
More data for this Ligand-Target Pair |